Question
Question: Reaction of ketoglutaric acid with ammonia to form glutamic acid is A. Oxidative amination B. Re...
Reaction of ketoglutaric acid with ammonia to form glutamic acid is
A. Oxidative amination
B. Reductive amination
C. Transamination
D. Ammonification
Solution
In human cells, this process takes approximately 15 to 20 minutes and results in the creation of a metaphase sheet.
Complete answer:
Glutamic acid is an amino acid that is used by nearly all living organisms in protein biosynthesis. It is not so essential in humans, which means that the body will synthesize it. Glutamic acid is an amino acid used to make proteins. It transforms into glutamate in the bloodstream. This is a chemical that allows nerve cells in the brain to transmit and retrieve input from other cells. It could be a function of learning and memory.
Amination is the mechanism by which the group of amines is incorporated into an organic molecule. This form of reaction is important as organonitrogen compounds are ubiquitous.
Reductive amination is the manner in which ammonium ions are assimilated to form amino acids in plants. In this reaction, in the presence of the enzyme glutamate dehydrogenase, the ammonium ion specifically interacts with alpha-ketoglutaric acid to form glutamic acid, and a reduced coenzyme is needed for this to happen.
Transamination is the mechanism by which amino acid groups are separated from amino acids and passed to acceptor keto acids to create the amino acid equivalent of keto acid and the keto acid equivalent of the original amino acid.
Ammonification is the mechanism by which microorganisms found in soil, sediment or water mineralize low molecular weight, remove organic molecules that found amine or amide groups and create ammonium.
Thus, the correct answer is option B. i.e., Reductive amination.
Note: Reductive amination is a type of animation that involves the conversion of a carbonyl group to an amine by an intermediate imine. The most famous group of carbonyl is ketone or aldehyde.