Question

Rathke's pouch is
A) Infundibulum
B) Hypophysis
C) Pituitary body
D) None of the above

Answer 1

In embryogenesis, Rathke's pocket is an evagination at the highest point of the making mouth before the buccopharyngeal layer. It offers to climb to the front pituitary (adenohypophysis), a bit of the endocrine framework.

Complete answer: Craniopharyngiomas (Rathke's pouch tumour) are formed from epithelial nests of the main cricopharyngeal canal (Rathke's pouch). Rathke's pouch is a diverticulum produced by the embryonic buccal cavity from which the anterior pituitary gland develops. Craniopharyngiomas are composed of well-differentiated epithelial components, including cysts and ameloblasts, and bones. Tumour is typically seen first intracranially, above the Turkish seal, and the pharyngeal portion is secondary. The hypophysis is a combination of two tissues. Early in gestation, an ectoderm finger grows up from the roof of the mouth. This protrusion is called Rathke's pouch and can grow into anterior pituitary or adenohypophysis. Around the same time as Rathke's pouch forms, another finger of the ectodermal tissue vaginates ventrally from the developing brain's diencephalon. This extension of the ventral brain becomes a posterior pituitary or neurohypophysis. At the end of the day the two tissues develop into one another and become closely applied, but their composition remains markedly different, representing their different embryological origins. The anterior wall of the pocket gives rise to the anterior lobe of the pituitary (pars distalis). The back wall of the pouch does not proliferate and remains the intermediate lobe of the pituitary (pars intermedia). The lumen of the pouch narrows to form a cleft (Rathke cleft) that usually recedes. The persistence of this cleft with the expansion is assumed to be the cause of the cleft cyst of Rathke (also known as pars intermedia cyst). During embryonic development, the diverticulum is developed from the roof of the buccal cavity of the embryo growing in front of the buccopharyngeal membrane. This diverticulum is called the Rathke pouch. It is ectodermal in nature and grows into a brain hypophysis. The hypophysis is sometimes referred to as the pituitary gland. Specifically, the Rathke pouch forms an adenohypophysis.
Thus, the right answer is option B.

Note: Rathke pouch, also known as a hypophyseal diverticulum, is an ectodermal outpouching of the stomodeum (primitive oral cavity lined with ectoderm) which forms at approximately 4 weeks of gestation and continues to form an adenohypophysis of the pituitary gland.