Question

Pepsin differs from trypsin in that it digests
A)Protein in the alkaline medium in the stomach.
B)Protein in acid medium in the stomach.
C)Protein in acid medium in duodenum.
D)Protein in alkaline medium in duodenum.

Answer 1

In order to promote its absorption by the body, digestive enzymes are a group of enzymes that break down polymeric macromolecules into their simpler building blocks. Digestive enzymes are present in the digestive tracts of animals (including humans) and in the tracts of carnivorous plants, where they promote food digestion, as well as within the cells, in particular in the lysosomes of animals, where they serve to sustain cellular life.

Complete answer:
Pepsin is secreted by the stomach's gastric glands. It is secreted in a shape called pepsinogen, which is inactive. It operates on and turns protein into proteoses and peptones. In an acidic medium, it catalyses. From the exocrine pancreas, trypsin is secreted. It is secreted in a shape called trypsinogen that is inactive. It acts on and turns proteoses and peptones into duodenum polypeptides. In an alkaline medium, it catalyses.

Proteolytic enzymes include both pepsin and trypsin. Pepsin is secreted in the intestine, while pancreatic juice is a part of trypsin. Pepsinogen is triggered by the application of pepsin to hydrochloric acid in the stomach. The optimal pH for pepsin activity is 1.8. Pepsin is an effective endopeptidase that breaks down proteins into smaller molecules such as peptones, peptides, and proteoses. Via the action of enterokinase, trypsinogen is activated into active trypsin. Enterokinase for trypsinogen activation is secreted by the duodenal mucosa. Trypsin and chymotrypsin are enzyme-type endopeptidases and are active at alkaline pH, i.e. 7.5 to 8. The proteins are dissociated into peptones and proteoses.

Hence, the correct answer is option (B)

Note: The principal gastric enzyme is Pepsin. It is produced in its inactive form, pepsinogen, which is a zymogen, by stomach cells called "chief cells'' Pepsinogen is then activated in its active form, pepsin, by stomach acid. Pepsin breaks down the food's protein into tiny pieces, such as fragments of peptides and amino acids. Therefore, protein digestion begins predominantly in the stomach, unlike carbohydrates and lipids that initiate digestion in the mouth (however, trace amounts of the enzyme kallikrein, which metabolises certain protein, is found in saliva in the mouth).