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Question

Pharmaceutics Question on Stability of formulated products

Noye-Whitney’s equation predicts:

A

An increase of dissolution rate if the particle size is reduced by micronization because of an increase in area

B

relationship between the radius of the diffusing molecule and its diffusion coefficient

C

The influence of electrolyte on the rate rate constant

D

An equilibrium between the surfactant and the drug molecules at the surface of the solution and in the bulk of the solution.

Answer

An increase of dissolution rate if the particle size is reduced by micronization because of an increase in area

Explanation

Solution

The correct option is (A): An increase of dissolution rate if the particle size is reduced by micronization because of an increase in area