Question

Net gain of ATP from one molecule of glucose in glycolysis is

• A. 3
• B. 6
• C. 8
• D. 2

Answer 1

Answer: (C)

8

Answer 2

In glycolysis, $2$ molecules of ATP are consumed initially in converting glucose to fructose $1 , 6$ -bisphosphate.
Four molecules of ATP are produced at substrate level phosphorylation, along with the generation of $2$ molecules of $NADH ^{+}$. These $NADH ^{+}$molecules are further utilized in the ETC to give rise to a total of $6$ molecules of ATP ($3$ ATP per $N A D H^{+}$).
Therefore, the net gain of ATP in glycolysis in aerobic organisms is $8$ ATP.