Question

Name a microbe used for statin production. How do statins lower blood cholesterol levels?

Answer 1

Microbes are microscopic living organisms that may be found all over the world but are too small to be seen with the human eye. They can be found in the water, the land, and the air. Millions of these bacteria, also known as microorganisms, live in the human body. Some bacteria make us ill, while others are necessary for our survival. Bacteria, viruses, and fungi are the most frequent kinds. Protozoa are another type of microorganism. These are microscopic organisms that cause illnesses including toxoplasmosis and malaria.

Complete answer:
Bacteria are creatures with only one cell. Some bacteria require oxygen to live, whereas others don't. Some people enjoy the heat, while others prefer the cold. Salmonella and Staphylococcus bacteria are two well-known bacteria types.
The majority of microorganisms are not harmful to humans. Many of them even live on or in our bodies, assisting us in maintaining our health. Lactic acid bacteria in the intestine, for example, aid in the digestion of food. Other bacteria aid the immune system by assisting in the battle against pathogens. Some bacteria are also required for the production of specific foods, such as yogurt, sauerkraut, and cheese.
Statins, also known as HMG-CoA reductase inhibitors, are a type of lipid-lowering medicine that helps people who are at high risk of cardiovascular disease live longer. They are the most often prescribed cholesterol-lowering medications.
The lipid hypothesis describes how cholesterol carriers in low-density lipoprotein (LDL) play a crucial role in the development of atherosclerosis and coronary heart disease. Statins are extensively used for primary and secondary prevention in persons at high risk of cardiovascular disease, as well as for those who have already established cardiovascular disease.
Statins are chemicals that block the activity of specific enzymes. Monascus purpureus is a common example of the organism responsible for statin manufacturing. It's a kind of yeast. Statins work by lowering cholesterol levels in the blood. Statins are drugs that prevent cholesterol from being formed by inhibiting enzymes involved in the process. Cholesterol does not develop as a result of this. As a result, the blood cholesterol level is decreased.

Thus,Monascus purpureus microbe is used for statin production.

Note:
Muscle discomfort, an increased risk of diabetes mellitus, and abnormal blood levels of liver enzymes are all side effects of statins. They also have several uncommon yet serious side effects, including muscular injury. They work by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis. Cardiovascular disease has been linked to high cholesterol levels.