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Question

Biology Question on Immune System

Monoclonal antibodies are produced from hybird cells, called hybridomas. The cells employed to obtain these hybridoma cells, are

A

B-lymphocytes and myeloma cells

B

Lymphoma cells and bone marrow cells

C

T-lymphocytes and myeloma cells

D

B-lymphocytes and carcinoma cells

Answer

B-lymphocytes and myeloma cells

Explanation

Solution

they are produced from the hybridoma cells of B lymphocytes and myeloma cells. The myeloma cells give them the property to grow uncontrollably and the B lymphocytes produce antibodies that are specific to one antigen. These monoclonal antibodies are generated using hybridoma technology. After the fusion of the cells, the selection is done in HAT media.