Question

Mention the use of statin.

Answer 1

Also known as HMG-CoA reductase inhibitors, the statins are a class of lipid-lowering medications which reduces mortality and illness to those who are at high risk of cardiovascular diseases. Statin has a significant impact if there is an underlying history of cardiovascular disease. Medication usage can be divided using this into broad categories of primary and secondary prevention.

Complete answer:
Statins are a type of medications that doctors give to help decrease cholesterol levels in the blood. Heart attacks and stroke can be prevented by lowering cholesterol levels. Different research studies show that, the use of statins reduce the risk of heart attack, stroke, and even death from heart disease in certain people by about $25\%$ to $35\%$.
Atorvastatin, lovastatin, Fluvastatin, pitavastatin, pravastatin, simvastatin and rosuvastatin are the various forms of statin. Combination preparations of a statin and another agent are available such as ezetimibe/simvastatin.
The statin works by blocking the action of liver enzymes which is responsible for production of cholesterol. There will be buildup of plaque on the walls of the arteries if there is too much cholesterol in blood. This can eventually cause the arteries to harden or narrow. When a sudden blood clot occurs in these narrowed arteries it can cause a heart attack or stroke.
Statins help to lower total cholesterol levels and LDL cholesterol. They lower triglycerides and raise HDL cholesterol levels at the same time. Statins may also help to make heart attacks less likely by stabilizing plaques in the arteries.

Therefore, Statin is used to lower cholesterol levels in blood.

Note:
Muscle pain, increased risk of diabetes mellitus, and abnormal blood levels of liver enzymes are the commonly seen side-effects. In addition, they have rare but severe adverse effects, which particularly includes muscle damage. The enzyme HMG-CoA reductase which plays a central role in the production of cholesterol is inhibited by statin. Cardiovascular disease is associated with high levels of cholesterol.