Question

Mention the exact location of Islet of Langerhans.

Answer 1

The islets of the pancreas are small islets of cells that produce hormones that regulate blood sugar levels. The hormones produced in the islets cells are secreted directly into the bloodstream by five different cell types. The location where the Islet of Langerhans is located develops from the endoderm of the embryo.

Complete answer:
The pancreas is lower than the stomach in duodenal flexion. The pancreas has both exocrine glands and endocrine glands. The large pancreatic duct runs through the gland and carries enzymes and other exocrine digestive secretions from the acinar cells of the pancreas to the small intestine.
The pancreas consists of nearly one million cell patches around blood capillaries known as Islets of Langerhans. These cells are endocrine.
So the location of the Islet of Langerhans in the pancreas.
Islet of Langerhans consists of five types of cells these are:
1.Alpha cells constitute fifteen to twenty percent of the total islet cells. Alpha cells produce glucagon is a peptide hormone, glucagon helps in maintaining the normal blood glucose levels glucagon is a hyperglycemic hormone. This hormone stimulates gluconeogenesis and glycogenolysis.
2.Beta cells constitute sixty to eighty percent of the total islets of Langerhans. Beta cells produce insulin that lowers blood glucose levels by promoting glycogenesis and enhancing cellular uptake and utilization of glucose. Insulin is a hypoglycemic hormone.
3.Delta cells constitute three to ten percent of the islet of Langerhans. Delta cells secrete the hormone somatostatin which inhibits the secretion of other horses from the pancreas.
4.Gamma cells constitute three to five percent of the islet of Langerhans they produce a hormone called pancreatic polypeptide that controls both endocrine and exocrine secretions of the pancreas.
5.Epsilon cells constitute less than one percent of the islet of Langerhans and produce protein ghrelin that stimulates hunger.

Note:
The cells of islets of Langerhans can communicate with each other through paracrine and autocrine mechanisms.
Diabetes Mellitus (Type first): It is also known as insulin-dependent diabetes mellitus mostly occurs in people younger than twenty. It is an autoimmune disorder in which the immune system destroys beta cells.
Diabetes Mellitus(Type second): It is noninsulin-dependent diabetes mellitus because this target cell became less sensitive to insulin. One of the reasons for this is obesity.