Question
Biology Question on Biomolecules
Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of
Amylase
Lipase
Dinitrogenase
Succinic dehydrogenase
Succinic dehydrogenase
Solution
Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of Succinic dehydrogenase.
Succinic dehydrogenase, also known as succinate dehydrogenase or succinate-coenzyme Q reductase, is an enzyme involved in the electron transport chain and the tricarboxylic acid (TCA) cycle in bacteria. It catalyzes the conversion of succinate to fumarate, playing a crucial role in energy production.
Melonate is a competitive inhibitor of succinic dehydrogenase. It structurally resembles succinate and competes with it for binding to the active site of the enzyme. By binding to and inhibiting succinic dehydrogenase, melonate disrupts the normal functioning of the TCA cycle and electron transport chain, leading to a decrease in ATP production and inhibiting the growth of pathogenic bacteria.
Therefore, the correct option is (D): Succinic dehydrogenase