Question

Match the items given in Column I with in Column II and select the correct options given below:

Column I	Column II
A. Fibrinogen	1. Osmotic balance
B. Globulin	2. Blood clotting
C. Albumin	3. Defence mechanism

A. A-1, B- 3, C-2 B. A-3, B-2, C-1 C. A-2, B-3, C-1 D. A-1, B-2 ,C-3

Answer 1

Plasma proteins are the proteins present in the blood plasma, so they are also called as blood proteins and there are many plasma proteins like globulin, albumin which have various functions and help in clinical diagnosis.

Complete answer:
Blood plasma proteins help in the transport of lipids, hormones and vitamins and minerals activity and they have a role in functioning of the immune system. Some plasma or blood proteins act as enzymes and are very crucial for the clinical diagnosis of related disease to this blood protein.
Plasma proteins like albumin have 55% of all the blood protein as it plays a crucial role in maintaining the osmotic pressure which is needed for the proper distribution of blood fluids between the blood vessels and body tissues. It also assists as a carrier in the transportation of lipids and steroid hormones. It is mainly known as serum albumin found in the blood of the vertebrates. Serum albumin is produced by the liver. It is dissolved in the blood plasma when it is formed. If there is no albumin present then the high pressure in the blood vessels would force more fluids out in the tissues.
The globulin has high molecular weight and is insoluble in pure water. Some globulins are produced in livers, while others are made from immune systems. Globulin contains 38% of plasma proteins which helps in the transport of ions and hormones and also lipids helps in assisting the immune function. The normal level of globulin present in the body is 2.0 to 2.5 gm/dl.
Fibrinogen is an extracellular protein present in the blood plasma of all vertebral species in large amounts. It is synthesised by the hepatocytes in the liver. During the formation of blood clots, the fibrinogen molecule is converted into fibrin by thrombin. It comprises 7% of all blood proteins which are helpful for the conversion of fibrinogen to insoluble fibrin, which is essential for blood clotting.

Hence, the correct answer is option (C).

Note: Plasma proteins can be separated by a process called electrophoresis and these values can be compared with the normal levels of the proteins which are helpful for the clinical diagnosis of various diseases related to these plasma proteins.