Question
Pharmaceutical Chemistry Question on Various classes of therapeutic agents
Match the antimalarial drugs with their modes of action
| (1) | Artemisinin | (P) | Inhibition of parasite mitochondrial electron Transport |
|---|---|---|---|
| (2) | Pyremethamine | (Q) | Inhibition of heme polymerase |
| (3) | Quinine | (R) | Generation of oxygen and carbon centered redicals |
| (4) | Atovaquone/Proguanil | (S) | Inhibition of dihydrofolate reductase |
A
1-P, 2-S, 3-Q, 4-R
B
1-Q, 2-S, 3-P, 4-R
C
1-S, 2-R, 3-Q, 4-P
D
1-R, 2-S, 3-Q, 4-P
Answer
1-R, 2-S, 3-Q, 4-P
Explanation
Solution
The correct option is (D): 1-R, 2-S, 3-Q, 4-P