Question
Biopharmaceutics and Pharmacokinetics Question on Bio-availability & Bio-equivalence
Match List I with List II | List I | List II | |
---|---|---|---|
A | When two dosage forms have equal t max | I | When their total body clearance is constant. |
B | AUC values of the two analogs can be compared to measure relative bioavailability | II | Absorption rate constants are equal |
C | Urinary data is valid to measure bioavailability. III. W | III | When fraction absorbed and elimination rate is constant. |
D | C max is proportional to the rate of absorption | IV | Excretion of drug and/or metabolite is related to the bioavailable dose. |
Choose the correct answer from the options given below:
A
A ‐ II, B ‐I , C ‐IV‐ , D ‐ III
B
A ‐I , B ‐II , C ‐III , D ‐IV
C
A ‐I, B ‐IV, C ‐III, D ‐II
D
A ‐III , B ‐I , C ‐II , D ‐IV
Answer
A ‐ II, B ‐I , C ‐IV‐ , D ‐ III
Explanation
Solution
The correct option is (A): A ‐ II, B ‐I , C ‐IV‐ , D ‐ III