Question
Physiology Question on Neurophysiology
Lesch–Nyhan syndrome is caused by deficiency of which enzyme?
A
Orotate Phosphoribosyltransferase
B
Uracil phosphoribosyltransferase
C
Quinolinate Phosphoribosyltransferase
D
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Answer
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Explanation
Solution
The Correct Option is (D):Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)