Question

Juxtaglomerular apparatus is made up of

• A. juxtaglomerular cells, macula densa and lads cells
• B. juxtaglomerular cells, Purkinje cells and chief cells
• C. juxtaglomerular cells, lads cells and myoepithelial cells
• D. juxtaglomerular cells, macula densa and argentaffin cells.

Answer 1

Answer: (A)

juxtaglomerular cells, macula densa and lads cells

Answer 2

Juxtaglomerular cells are the smooth muscle cells of both the afferent and efferent arterioles that are swollen and contain dark granules. These cells secrete renin. In these specialized cells, the afferent arteriole comes in contact with the distal convoluted tubule.

• Macula densa are the epithelial cells of the distal convoluted tubule that come in contact with the afferent and efferent arterioles.
• These cells are more dense than the other tubular cells. They act as chemoreceptors.
• Lads cells are located between the macula densa and the afferent and efferent arterioles.
• The function of lacis cells is unknown.
• All these cells make up the juxtaglomerular apparatus.

Therefore, The Juxtaglomerular apparatus comprises the Juxtaglomerular cells, macula densa and lacis cells. So, the correct answer is Option A.

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