Question

Is Trypsin the same as Trypsinogen?

Answer 1

Trypsin is an enzyme which is helped to digest the protein. In the small intestine trypsin breaks the protein. After that it continues the process of digestion which began in the stomach. It is done by the proteolytic enzyme or proteinase. It speeds up the biochemical reaction. It is made from fungus, plants and bacteria. The leguminoseae family possesses lots of trypsin levels. Trypsin is the medium size globular protein.

Complete answer:
Trypsin is an enzyme which is used to digest protein. It is also called as the proteolytic enzyme. Pancreas produces the inactive enzyme called as the trypsinogen. So trypsinogen is in the inactivated form and activated by the enterokinase in small intestine. Enteropeptidase is also named as enterokinase. It is produced by the mucosa of duodenum. Trypsinogen is the pro enzyme precursor of trypsinogen. It is firstly available in the pancreas in the non activated form and then activated by the enzyme. Auto activation is the process of converting the trypsin and trypsinogen. The peptide bond splits in the carboxyl side of amino acids such as arginine and lysine in trypsin.
Trypsinogen has a proteolytic activity. It is the reason for self activation of the trypsinogen. This process is called the trypsinogen activation. It is catalyzed slowly by the trypsinogen and then the remaining of them activated by the trypsin. During the acute pancreatitis process enzymes in the pancreas are moved into the blood. Trypsin also moves towards the blood. It is made by trypsinogen. After that it will be converted into trypsin in the small intestine. Trypsinogen is produced at the need of the protein digestion process.

Note:
Pancreas only stores the inactive form of trypsinogen because active form of trypsin may damage the tissue of pancreas. Increased levels of trypsinogen may be the reason for abnormal production of pancreatic enzymes. Trypsin is also used as the painkiller. It will break the protein into smaller particles or fragments. This produced molecule is absorbed by the blood. It increases the blood supply at the affected area and reduces the swelling.