Question
Biology Question on Enzymes
Inhibition of Succinic dehydrogonase enzyme by malonate is a classical example of:
A
Cofactor inhibition
B
Feedback inhibition
C
Competitive inhibition
D
Enzyme activation
Answer
Competitive inhibition
Explanation
Solution
Malonate is a competitive inhibitor of the enzyme succinic dehydrogenase. It competes with the substrate, succinate, for the active site of the enzyme. In competitive inhibition, the inhibitor resembles the substrate and binds to the enzyme’s active site, preventing the normal substrate from binding.