Question
Question: In which of the following parts of mitochondria succinic dehydrogenase enzyme is located? A. Peri ...
In which of the following parts of mitochondria succinic dehydrogenase enzyme is located?
A. Peri Mitochondrial space
B. Outer membrane
C. Matrix
D. Inner membrane
Solution
Succinic Dehydrogenase is a complex enzyme.
It is the only enzyme which participates in both citric acid cycle and the electron transport chain.
Mitochondria helps in manufacturing of energy in the form of ATP. Mitochondria is specifically stained with janus green.
Complete answer:
Mitochondria are not seen under the microscope unless specifically stained.
The number of mitochondria per cell depends upon physiological activity of cells.
It is sausage shaped or cylindrical in shape having a diameter of 0.2 to 1.o nanometer.
Mitochondria are a double layered structure with outer and inner membrane which divides the lumen into two aqueous compartments.
Outer compartment forms the limiting boundary of the organelle.
Inner compartment forms a number of folds known as cristae towards the matrix.
These two membranes are associated with their own specific enzymes with their mitochondrial function.
Mitochondria are sites of aerobic respiration.
They produce energy in the form of ATP that’s why it is known as a powerhouse of cells.
So, according to the question, SDH or Succinate dehydrogenase or respiratory complex 2 is an enzyme complex found in many bacterial cells and in the inner mitochondrial membrane of the eukaryotic cells.
It is the only enzyme which participates in both the citric acid cycle and the electron transport chain.
In the 6th step of the citric acid cycle, SQR catalyzes the oxidation of succinate to fumarate with reducing the ubiquinone to ubiquinol.
This process occurs in the inner mitochondrial membrane by the coupling of the reactions.
So, the correct option is option D. Inner membrane.
Note: The succinate-binding site and ubiquinone-binding site are connected by a chain of redox centers including FAD and the iron-sulfur clusters.
The binding site for succinate is SdhA.
The side chains Thr254, His354, and Arg399 of the sub unit.
A stabilizes the molecule while FAD oxidizes and carries the electrons to the first of the iron-sulfur cluster.