Question

In Hashimoto's disease, symptoms develop like
a. Hyposecretion of thyroxine
b. Hypersecretion of thyroxine
c. Hyposecretion of adrenaline
d. None of the above

Answer 1

Hashimoto disease the symptoms develop like the secretion of a certain hormone that is released by the thyroid gland (the largest endocrine glands in humans). The symptoms of this disease include weight gain, muscle pain, and irregularity in the menstrual cycle, etc. due to deficiency of the hormone.

Complete answer:
• Hashimoto disease or auto-immune thyroiditis is a disease that causes hypothyroidism. It is a disease that causes less secretion of thyroid hormone or thyroxine.
• In this condition, the immune system of the human body attacks the thyroid gland. Due to the inflammation of the thyroid gland, it becomes less active and there is less secretion of the thyroxine.
• The symptoms of this disease include weight gain, muscle pain, depression, slower heart rate, irregularities in the menstrual cycle, constipation, dry and thinning hair, fatigue, pale and puffy face, depression, problems in pregnancy, etc.

Also,
• Hypersecretion of thyroxine i.e. more secretion of thyroid hormone causes diseases like:
• Grave's disease
• Plummer's disease (enlargement of thyroid gland along with nodules)
• Exophthalmic goiter
• Hyposecretion of adrenaline i.e. less secretion of adrenaline hormone (emergency hormone) may limit the ability of the body to respond in a stressful situation. This occurs rarely.

Hence, the correct answer is option (A).

Note: As Hashimoto disease causes less secretion of thyroid hormone, there are various factors which cause risk for developing this disease like- women are more prone to this disease, it commonly occurs in the middle age, it is also associated with the heredity, exposure to radiation, having other auto-immune diseases, etc.