Question

In a pedigree analysis the following diagram represents.

A. Unrelated mating
B. Consanguineous mating
C. Affected parents
D. Siblings
E. Non-identical twins

Answer 1

To research the inheritance of genes in humans, scientists have invented another method , called pedigree analysis. Analysis of pedigree is also helpful when researching any population when data on progeny from many generations is limited. In the study of species with a long generation span, pedigree analysis is also helpful.

Complete solution:
All the available information about the inheritance of a single trait within a family is represented by the Ach pedigree table. Therefore, the pedigree chart is drawn using factual information, but there is always some likelihood of mistakes in this information , especially when relying on the recollections of family members or even clinical diagnoses. Further problems which occur in real pedigrees due to incomplete penetrance and variable expressivity of disease alleles, but we will assume full precision of the pedigrees for the examples given in this book. When attempting to ascertain the essence of a newly discovered disease, or when a person with a family history of a disease wants to know the likelihood of passing the disease on to their offspring, a pedigree might be drawn. A tree is drawn in either case, with circles to represent women, and squares to represent males. Matings are drawn as a line that connects a male and a female, while two lines are closely related to consanguineous mating.

Hence, Option B is the right answer.

Additional Information:
Consanguinity is both a definition of social and genetic heritage. It usually refers to marriage or a reproductive partnership between two individuals who are closely related. The degree of association between two people determines the proportion of genes that are shared between them. Owing to their increased risk for homozygosity through descent, the offspring of consanguineous pairs are at increased risk for autosomal recessive disorders.

Note: When a provider is unaware of the existence of consanguinity at the time they analyse the pedigree, consanguinity may complicate pedigree study, and what appears to be an autosomal dominant inheritance pattern is correlated with a phenotype of autosomal recessive disease.