Question

Hyposecretion of growth hormone causes
A)Acromegaly
B)Cretinism
C)Dwarfism
D)Myxoedema

Answer 1

Hyposecretion is the development of no hormone or of a hormone that is too tiny. It may be caused by the death of cells that secrete hormones, such as in type 1 diabetes, or by a nutritional deficiency that is necessary for the synthesis of hormones. Hyposecretion with hormone-replacement therapies can be treated.

Complete answer:
A. Acromegaly is a hormonal condition that develops in adults due to growth hormone oversecretion.

B. The retarded emotional and physical growth due to thyroid hormone hypersecretion is cretinism.

C. Dwarfism is caused by growth hormone hyposecretion during the time of skeletal growth.

D. Myxoedema, referred to as Gull's disease typically develops in adults after full physical and behavioral growth due to thyroid hormone deficiency.

Growth hormone (GH) or somatotropin is a single chain peptide hormone having 191 amino acids. It is known to promote growth, cell replication, and cell regeneration in humans and other species, often referred to as human growth hormones (hGH or HGH). GH also induces IGF-1 development and increases glucose and free fatty acid concentrations. It is a kind of mitogen that on certain types of cells is unique only to the receptors.

Hence, the correct answer is option (C)

Note: In the fifth decade of life, GH-secreting tumours are usually recognised. It is exceedingly unlikely for such a tumor to develop in infancy, but when it does, excessive GH, historically referred to as pituitary gigantism, can cause excessive growth. The bones of the chin, fingers and toes are thickened by excessive excess GH, resulting in jaw heaviness and increased digit size, referred to as acromegaly.