Question

How many of the following diseases can be studied with the help of a pedigree chart?
Turner's syndrome, Phenylketonuria, Down's syndrome, Sickle cell anaemia, Klinefelter's syndrome, Haemophilia, Cystic fibrosis, Myotonic dystrophy.
A. ALL
B. 6
C. 5
D. 4

Answer 1

A pedigree chart is a chart that is used to study genetic disorders and it represents the information regarding the inheritance of a single gene within a family.

Complete answer:
A pedigree chart is a diagram or a method that shows phenotypes/ genotypes for a particular organism and its ancestors or you can simply say a pedigree chart represents all the information about the inheritance of a single trait within a family. It is a method to study human genetic disorders and to solve this question we need to find out human genetic disorders and the total genetic disorders given in the questions will be the final answer.
Let's look at Turner's syndrome. It is a rare genetic disorder which is found only in females. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Phenylketonuria is an autosomal recessive disorder which is caused by mutation in both alleles of genes found on chromosome 21 and this genetic disease can be studied with the help of a pedigree chart.
Down's syndrome is also a genetic disorder and this disorder is caused by the presence of a third copy of chromosome 21. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Sickle cell anaemia is also a genetic disorder where there is production of abnormal haemoglobin S by the body. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Klinefelter's syndrome is also a genetic condition which is caused by the presence of an extra copy of X chromosome. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Haemophilia is also a genetic disorder caused by mutation in genes located on X chromosome. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Cystic fibrosis is also a genetic disorder which affects lungs and digestive system. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Myotonic dystrophy is also a genetic disorder which affects muscles and other body systems. Since it is a genetic disorder then this disease can be studied with the help of a pedigree chart.
Since, all the disorders given are genetic disorders and therefore all these disorders can be studied with the help of a pedigree chart.
Thus, the correct answer is Option A i.e., All.

Note: Since Turner's syndrome, Phenylketonuria, Down's syndrome, Sickle cell anaemia, Klinefelter's syndrome, Haemophilia, Cystic fibrosis and Myotonic dystrophy are genetic disorder, all these can be studied with the help of pedigree chart and therefore the correct option is A i.e., All.