Question
Question: How many ATP are produced when one molecule of \(FAD{H_2}\) is oxidized to FAD through an electron t...
How many ATP are produced when one molecule of FADH2 is oxidized to FAD through an electron transport system?
A. 2
B. 3
C. 1
D. 4
Solution
FADH2 is involved in the electron transport chain. Electron transport chain-ETC is located in the inner mitochondrial membrane. The inner mitochondrial membrane has groups of several proton (H+) and electron (e−) acceptors, which are arranged in series called Electron Transport chain (ETC).
Complete Answer:
The various components of electron transport system includes:
Cytochrome b, 2 types of cytochrome C, Ubiquinone, flavoprotein (FMN or FAD), Fe−Sprotein (Fe−S) and enzyme cytochrome oxidase. These components are arranged in four kinds of complexes:
A) Complex I (NADH dehydrogenase complex).
B) Complex II (Succinate dehydrogenase complex).
C) Complex III (Cytochromebc1, complex).
D) Complex IV (Cytochrome oxidase complex).
E) A fifth complex, ATP synthase complex is also there (oxidative phosphorylation).
During Krebs cycle two hydrogens removed from succinate reduce FAD to FADH2. This FADH2 enters through Complex II into the electron transport system (ETS), at this stage by transferring its 2H to Ubiquinone (UQ) the UQ is reduced to UQH2. They are oxidised during ETC and used for ATP synthesis.
The correct option is (A) 2.
Note: The enzyme involved in ETC oxidase is tightly bound to the inner mitochondrial membrane. This contains inseparable Cyt a and Cyt a3 components and also some polypeptide that contain two Cu ion.
3 ATP are formed for every pair of electrons that enter by way of NADH and 2 ATP are formed that enter by way of FADH2.
Complex V i.e. ATP synthase complex is involved in ATP synthesis.