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Question: How many ATP are produced when one molecule of \(FAD{H_2}\) is oxidized to FAD through an electron t...

How many ATP are produced when one molecule of FADH2FAD{H_2} is oxidized to FAD through an electron transport system?
A. 22
B. 33
C. 11
D. 44

Explanation

Solution

FADH2FAD{H_2} is involved in the electron transport chain. Electron transport chain-ETC is located in the inner mitochondrial membrane. The inner mitochondrial membrane has groups of several proton (H+{H^ + }) and electron (e{e^ - }) acceptors, which are arranged in series called Electron Transport chain (ETC).

Complete Answer:
The various components of electron transport system includes:
Cytochrome b, 2 types of cytochrome C, Ubiquinone, flavoprotein (FMN or FAD), FeSFe - Sprotein (FeSFe - S) and enzyme cytochrome oxidase. These components are arranged in four kinds of complexes:
A) Complex I (NADH dehydrogenase complex).
B) Complex II (Succinate dehydrogenase complex).
C) Complex III (Cytochromebc1b{c_1}, complex).
D) Complex IV (Cytochrome oxidase complex).
E) A fifth complex, ATP synthase complex is also there (oxidative phosphorylation).

During Krebs cycle two hydrogens removed from succinate reduce FAD to FADH2FAD{H_2}. This FADH2FAD{H_2} enters through Complex II into the electron transport system (ETS), at this stage by transferring its 2H to Ubiquinone (UQ) the UQ is reduced to UQH2UQ{H_2}. They are oxidised during ETC and used for ATP synthesis.

The correct option is (A) 22.

Note: The enzyme involved in ETC oxidase is tightly bound to the inner mitochondrial membrane. This contains inseparable Cyt aCyt{\text{ }}a and Cyt a3Cyt{\text{ }}{a_3} components and also some polypeptide that contain two CuCu ion.
3 ATP are formed for every pair of electrons that enter by way of NADH and 2 ATP are formed that enter by way of FADH2FAD{H_2}.
Complex V i.e. ATP synthase complex is involved in ATP synthesis.