Question

Hexose monophosphate pathway takes place in-
A. Mitochondrial matrix
B. Cristae
C. Cytoplasm
D. E.R

Answer 1

In the same place as glycolysis, the hexose monophosphate pathway occurs. It has been shown to be a significant regulator for homeostasis and biosynthesis of cellular reduction-oxidation (redox).

Complete answer:
Option A is incorrect. Mitochondrial metabolic pathways (TAC cycle, beta oxidation, and haem synthesis) are regulated by the mitochondrial matrix, and electron transport chain complexes and ATP synthase are found in the inner membrane. Also important are exchange carriers such as the malate-aspartate shuttle.
Option B is incorrect. On this membrane, the electron transport chain and chemiosmosis take place as part of cellular respiration to produce ATP. As the cristae expand the inner membrane surface area, it allows ATP to be produced more quickly since there are more places to conduct the operation.
Option C is correct. The hexose monophosphate shunt reactions happen primarily in the cytoplasm and are an additional glucose metabolism pathway that begins with glucose-6-phosphate. This pathway metabolises between 10-25% of glucose. In plants, it occurs in both plastids and cytosols. Oxidative and nonoxidative steps are involved in this pathway. NADPH and ribose-5-phosphate are produced by the oxidative steps and then ribose-5-phosphate is converted back into glucose-6-phosphate by non-oxidative steps, which can be further exploited by oxidative steps for NADPH generations.
Option D is incorrect. In the ER, many metabolic routes are compartmentalised. The active core of the participating enzymes is, in particular, localised in the lumen. These pathways are related to the metabolism of carbohydrates, biotransformation, metabolism of steroids and protein processing.

So, the correct answer is Option C.

Note: An alternative pathway to glycolysis is the HMP (hexose monophosphate shunt) shunt, which is used to manufacture ribose-5-phosphate and nicotinamide adenine dinucleotide phosphate (NADPH). This pathway does not use ATP or oxygen and only 1 ATP per glucose molecule is usually the net yield of ATP for this pathway.