Question

Hepatitis-B vaccine is
A. First generation vaccine
B. Second generation vaccine
C. Third generation vaccine
D. Fourth generation vaccine

Answer 1

An infectious disease caused by a virus named hepatitis B virus (HBV) is called hepatitis B. This virus causes serious infection to the liver but can be cured easily by vaccination. The vaccine used to treat hepatitis B infection is known as the hepatitis B vaccine.

Complete answer: The hepatitis B virus primarily attacks the liver but can also cause both acute and chronic diseases. The spread of the virus is mostly through body fluids such as blood, semen, and saliva. Chronic infections of hepatitis B cause liver failure, liver cancer, or cirrhosis. Cirrhosis refers to a condition of a permanent scar on the liver. Hepatitis B vaccine is used for the purpose of treatment of the infection. Hepatitis B vaccine is a type of second-generation vaccine. Second-generation vaccines are those that are prepared by using the technique called genetic engineering. These vaccines are prepared to contain subsections in the form of proteins or toxoids. Second generation vaccines were developed in the second half of the twentieth century. Various improvements and development in innovation in mammalian cell culture technology led to the growth of viruses and the formation of second-generation vaccines. Therefore, option B: the second-generation vaccine is the correct answer as the hepatitis B vaccine is an example of a second generation vaccine.
So, option B is the correct option.

Note: BCG vaccine is an example of a first-generation vaccine. These vaccines are prepared by using heat-killed pathogens. Third generation vaccines are a type of artificially synthesized vaccines. These vaccines contain recombinant vector vaccines in which antigen is a subunit of the pathogen. An example of a third-generation vaccine is the Ebola vaccine.