Question
Question: Growth hormone (GH) or STH is secreted by A. Adrenal B. Anterior lobe of pituitary C. Posterio...
Growth hormone (GH) or STH is secreted by
A. Adrenal
B. Anterior lobe of pituitary
C. Posterior lobe of pituitary
D. Sex organs
Solution
Hint:- Growth hormone is also called as Somatotropin and it is peptide hormone which
stimulates the growth, cell reproduction, and cell regeneration in humans and other animals, and it is
the hormone that is important in human growth and development.
Complete step-by-step solution:- 1. The growth hormone is a peptide hormone that is synthesized, stored, and secreted in the anterior lobe of the pituitary.
2. The main function of growth hormone is to induce height in the children and adolescents, apart
from this growth hormone has many other functions.
3. It increases the retention of calcium which in turn increases the strength and mineralization of
bone.
4. It also increases muscle mass by sarcomere hypertrophy.
5. It promotes lipolysis and plays an important role in homeostasis.
Excessive secretion of growth hormone results in two conditions, based on the age of the person.
Excessive secretion of growth hormone in the children, which are of growing produce a condition called
gigantism, and the excessive secretion of growth hormone in the adults after the close of growth plates
results in acromegaly.
Gigantism: There are so many reasons for the excessive secretions and most common reason is any
adenoma of the pituitary, commonly growth producing age is 13 years, and it is different in males and
female, where the grow in abnormal height, and in some pediatric patients there are some
complications such as hypertension may present.
Acromegaly: Acromegaly is the condition where the pituitary gland secretes the more growth hormones
after the closing of growth plates or in the adults, mostly these hyper secretions are due to adenoma of
the pituitary gland.Due to this excessive secretion of growth hormone, there are some initial symptoms that include the enlargement of hands and feet and at the same time, there is an enlargement of the
forehead, jaws, and nose.If the secretions become more, then the severity of symptoms increases.The person may have a more severe and profound headache.And other complications include hypertrichosis, and hyperpigmentation, and Carpal tunnel syndrome.Dwarfism: hypersecretion of growth hormone in child, and adolescents, where the growth plates are fused early, and in this person there is stunted physical growth.
So from the above explanation, the correct option is B..
Note:- In case of any need and necessary of the growth hormone, a recombinant form of the human growth hormone which is called as somatreopleopin which is used as medicine to treat the child growth disorders and also to treat the adult growth hormone deficiency.