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Question

Pharmacy Question on Drugs

Glutathione (GSH) conjugation takes place by

A

Electrophilic attack by GSH on nucleophilic carbon of drugs

B

Nucleophilic attack by GSH on electrophilic carbon of drugs

C

Photochemical reaction of GSH with the drug molecule

D

lonic reaction of GSH with the drug molecule

Answer

Nucleophilic attack by GSH on electrophilic carbon of drugs

Explanation

Solution

The correct option is(B): Nucleophilic attack by GSH on electrophilic carbon of drugs