Question

Given below are two statements
Statement I : RNA interference takes place in all Eukaryotic organisms as method of cellular defense.
Statement II : RNAi involves the silencing of a specific mRNA due to a complementary single-stranded RNA molecule that binds and prevents translation of mRNA
In the light of the above statements, choose the correct answer from the options given below

• A. Statement I is true but Statement II is false.
• B. Statement I is false but Statement II is true.
• C. Both Statement I and Statement II are true.
• D. Both Statement I and Statement II are false.

Answer 1

Answer: (A)

Statement I is true but Statement II is false.

Answer 2

Statement I: RNA interference (RNAi) is a mechanism found in many eukaryotic organisms that is used as a cellular defense mechanism against viruses and other foreign genetic material. It also plays a role in regulating gene expression. Thus, Statement I is true.
Statement II: RNAi involves the silencing of mRNA by double-stranded RNA (dsRNA), not single-stranded RNA (ssRNA). The dsRNA is processed into small interfering RNAs (siRNAs), which then guide the RNA-induced silencing complex (RISC) to the target mRNA. The RISC cleaves the target mRNA, leading to its degradation and preventing translation.
Thus, statement II is false.