Question

Frameshift mutation occurs when

• A. base is subsituted
• B. base is deleted or added
• C. anticodons are absent
• D. none of these

Answer 1

Answer: (B)

base is deleted or added

Answer 2

Frameshift mutation occurs when one or more nucleotides are either added or deleted from DNA. Example of frameshift mutation due to deletion is as follows: Original (wild type) message or reading frame $\quad\quad$ CAT $\quad$ GAT $\quad$ CAT $\quad$ GAT $\quad$ CAT $\quad$ GAT $\quad$ CAT After Deletion $\quad\quad$ CAT $\quad$ GAT $\quad$ ATG $\quad$ ATC $\quad$ ATG $\quad$ ATC $\quad$ AT Message out of frame