Question

for acetalization which alcohol is more favourable meoh or t-buoh

Answer 1

Methanol (MeOH) is more favorable for acetalization due to less steric hindrance compared to tert-Butanol (t-BuOH).

Answer 2

Acetalization involves the nucleophilic attack of an alcohol on the electrophilic carbonyl carbon of an aldehyde or ketone. Methanol (MeOH) has minimal steric hindrance due to its small methyl group, whereas tert-Butanol (t-BuOH) has significant steric hindrance due to its bulky tert-butyl group. Therefore, methanol is more favorable for acetalization.