Question
Biology Question on body fluids and circulation
Examination of blood of a person suspected of having anaemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supplementing his diet with which of the following, is likely to alleviate his symptoms ?
Thiamine
Folic acid and cobalamine
Riboflavin
Iron compounds
Folic acid and cobalamine
Solution
Large, immature, nucleated erythrocytes without hemoglobin are characteristic of megaloblastic anemia, which can be caused by deficiencies in folic acid (vitamin B9) and cobalamin (vitamin B12). Supplementation with these vitamins can help improve the production of normal red blood cells and alleviate the symptoms of megaloblastic anemia. Iron compounds (option D) are typically used to treat other forms of anemia, such as iron-deficiency anemia.
So, the correct option is (B): Folic acid and cobalamine