Question

Epicanthal skin fold and simian crease are characteristics of
A. Down’s syndrome
B. Klinefelter’s syndrome
C. Thalassemia
D. Turner’s syndrome

Answer 1

The single palmar crease is indeed a deep, simple, crease, frequently alluded to as a simian crease, in the palm.

Complete Answer:
A genetic disease is a health condition that is induced by one or more genome defects. It may be caused by a monogenic or polygenic gene mutation or through a chromosomal abnormality. While polygenic disorders are the one of the most prevalent, when describing disorders with a particular genetic origin, whether in a gene or chromosome, the term is frequently used.

Now, let us find the solution from the options-
- Down's syndrome is a concern with inherited genes. John Langdon Down first mentioned it in 1866. Trisomy at 21, e.g the occurrence of chromosome 21 in three copies, is anyone with Down syndrome. It is an autosomal condition that is characterised by the outward slanting eyes that have an additional skin fold on the upper eyelid recognized as an epicanthal fold. The inner corner of their eye adjacent to their nose is hidden by this skin fold.
- The series of symptoms that arise from two or more X chromosomes in males is Klinefelter syndrome (KS), also referred to as 47,XXY. Infertility and thin, poorly working testicles are the main characteristics. Symptoms are always gradual and participants do not feel if they are affected. Thus, option B is not the correct answer.
- Thalassemias are hereditary blood diseases and are characterised by diminished development of haemoglobin. Symptoms differ on the form and can range from none to serious. Thus, option C is not the correct option.
- Turner syndrome (TS), also recognized as 45,X, or 45,X0, is a genetic disorder in which the X chromosome is partially or entirely absent in a person. For those impacted, signs and symptoms differ. Thus, option D is not the correct option.

Thus, the correct answer is option (A) Down’s syndrome.

Note: Down syndrome does not have a cure. It has been shown that education and proper treatment increase the quality of life. In traditional school classrooms, some children with Down syndrome are taught, while others need more advanced instruction.