Biology Question on Molecular Basis of Inheritance

Question

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called?

Answer 1

Solution

A TATA box is a specific DNA sequence that serves as a marker for where a genetic sequence can be interpreted and decoded. This sequence acts as a promoter, initiating the transcription process. The name "TATA box" originates from its well-preserved DNA sequence, which is typically TATAAA. In numerous eukaryotic genes, this conserved TATA box is situated 25-35 base pairs before the gene's transcription start site. The TATA box has the capacity to establish the direction of transcription and identifies the DNA strand that should be read. Recognition of the TATA box is carried out by the TATA-binding protein, or TBP, which directly attaches to the TATA box. TBP achieves this connection by folding its DNA binding domain into a semi-symmetrical saddle shape, with the DNA positioned between the two sides of the saddle.

so, the correct option is (D): TATA Box