Question

During chain elongation peptide bond is formed between carboxyl group of Ist amino acid and amino group of 2nd amino acid by

• A. Aminoacyl transferase
• B. Peptidyl transferase
• C. Aminoacyl synthetase
• D. Chloramphenicol

Answer 1

Answer: (B)

Peptidyl transferase

Answer 2

During translation, elongation of polypeptide takes place by regular addition of different amino acids. Formation of first and subsequent peptide bond occurs
between free-COOH group of peptidyl tRNA at P site and free $NH_2$ group of aminoacyl tRNA at A site with the help of peptidyl transferase enzyme.