Question
Biopharmaceutics and Pharmacokinetics Question on Bio-pharmaceutics
Drugs that show nonlinear pharmacokinetics have which of the following property
A
A constant ratio of drug metabolites is formed as the administered dose increase.
B
The elimination half-life increasing as the administered dose increase
C
The area under the plasma drug concentration versus time curve increasing in direct proportion to an increase in the administered dose.
D
Both low and high doses follow first order elimination kinetics
Answer
The elimination half-life increasing as the administered dose increase
Explanation
Solution
The correct option is (B) : The elimination half-life increasing as the administered dose increase