Question

Distinguish between glycolysis and krebs cycle.

Answer 1

Glycolysis is the process by which one molecule of glucose is converted into two molecules of pyruvate, two hydrogen ions, and two molecules of water. The Krebs cycle is also called the TCA cycle or the citric acid. It is a series of chemical reactions used by aerobic organisms to release stored energy through the oxidation of Acetyl-CoA, which are derived from carbohydrates, fats, and proteins.

Complete answer:

Glycolysis	Krebs Cycle
It is the first step of respiration yielding two molecules of pyruvic acid after the partial breakdown of a glucose molecule in a set of enzymatic processes	Krebs Cycle is the second step of aerobic respiration in which pyruvate is oxidized completely into inorganic substances forming carbon dioxide
Anaerobic process	Aerobic process
Occurs inside the cytoplasm	Occurs inside the mitochondria
Partial breakdown of Glucose to Pyruvic acid	Complete oxidation of Pyruvate to release Carbon dioxide
No carbon dioxide evolved	Carbon dioxide evolved
Oxygen is not required for glycolysis	Oxygen is required
Four ATP molecules are produced in the glycolysis for each glucose molecule	One ATP or GTP molecule is produced by substrate-level phosphorylation in each turn of the Krebs cycle
Consumes 2 molecules of ATP for initial phosphorylation of substance molecules	Doesn’t consume ATP

Note: The transition reaction, in between the two cycles, connects glycolysis to the citric acid (Krebs) cycle. The reaction converts- two molecules of the 3-carbon pyruvate from glycolysis (and other pathways) into two molecules of the 2-carbon molecule acetyl Coenzyme. An (Acetyl-CoA) and 2 molecules of carbon dioxide. In Glycolysis, there is a total gain of four ATP molecules and two molecules of NADH. At the end of the Krebs cycle, there is a total gain of two GTP, six NADH, two QH2, and four $CO_2$