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Question

Biology Question on the molecular basis of inheritance

Discontinuous synthesis of DNADNA occurs in one strand, because

A

DNADNA molecule being synthesised is very long

B

DNADNA dependent DNADNA polymearse catalyses polymerisation only in one direction (53)(5' \rightarrow 3')

C

it is a more efficient process

D

DNADNA ligase has to have a role

Answer

DNADNA dependent DNADNA polymearse catalyses polymerisation only in one direction (53)(5' \rightarrow 3')

Explanation

Solution

The DNADNA-dependent DNADNA polymerases catalyse polymerisation only in the one direction, that is 535' \rightarrow 3'. This creates some additional complications at the replicating fork. Consequently, on one strand (the template with polarity 353'\rightarrow 5'), the replication is continuous, while on the other (the template with polarity 535' \rightarrow 3'), it is discontinuous. The discontinuously synthesised fragments are later joined by the enzyme DNADNA ligase.