Question
Question: Deficiency of VIII factor leads to A. Haemophilia A B. Haemophilia B C. Haemophilia C D. Hae...
Deficiency of VIII factor leads to
A. Haemophilia A
B. Haemophilia B
C. Haemophilia C
D. Haemophilia D.
Solution
In factor to VIII deficiency the body does not make enough factor VIII (factor 8), one of the substances the body needs to form a clot. The normal ranges for factor VIII ranges are 50% to 150%.
Complete answer:
To answer this question, first, we need to know about the factor VIII. Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene result in hemophilia A, a recessive X attached coagulation disorder. Factor VIII occurs in liver endothelial cells and sinusoidal cells outer of the liver all over the body.
Now, let us find the solution from the option.
Hemophilia A is the usual kind of hemophilia and it occurs due to the shortage in factor VIII.
Hemophilia B that is additionally known as Christmas disease, occurs because of lack of factor IX.
Hemophilia C is a mild form of the disease which occurs by shortage of factor XI.
Thus, the correct option is A .i.e. Haemophilia A.
Note: Hemophilia A is the most usual intense bleeding disorder. Von Willebrand disease is the most common among all other bleeding disorders. Blood doesn't clot in the proper way in hemophilia A. This causes a person at danger of uncontrolled blood loss. In normal conditions, some proteins, like factor VIII, come together to produce blood clots and instantly prevent blood loss.