Question
Biology Question on chemical coordination and integration
Cortisol is secreted by the adrenal cortex in response to stress. In addition to its function in a stress response, it functions in negative feedback by
A
inhibiting the hypothalamus so that Corticotropin Releasing Hormone (CRH) secretion is reduced
B
inhibiting the anterior pituitars ability to respond to CRH by reducing the pituitarys sensitivity to CRH
C
Both (a) and (b)
D
None of the above
Answer
Both (a) and (b)
Explanation
Solution
Cortisol and corticosterone are the main glucocorticoids secreted from adrenal cortex. Their secretion is stimulated by ACTH from the anterior pituitary and by stress.