Question
Question: Convert ethanoic acid into methanamine?...
Convert ethanoic acid into methanamine?
Solution
There is use of alkali as a strong base in Hoffman bromamide reaction to attack amide. It leads to formation of anion which happens after deprotonation. This reaction basically is best to convert primary amide into a primary amine, which proceeds with reduction of one carbon.
Complete answer:
Convert ethanoic acid into methanamine:
First step: Convert Ethanoic acid into ethyl acyl chloride. We will react with ethanoic acid with SOCl2 , it will give us CH3COCl . Which is Ethanoyl chloride.
CH3COOHSOCl2CH3COCl
Second Step: In the second step we will convert acyl chloride into acetamide with ammonia in excess.
CH3COClNH3(excess)CH3CONH2
Third step: Conversion of acetamide into methanamine in presence of bromine or Alkali hydroxide
With the help of Hoffmann bromamide reaction.
CH3CONH2Br2/KOHCH3NH2
Additional knowledge: Acetic acid or ethanoic acid is a weak carboxylic acid. It is the chief acetic acid. The acetic acid formula represents two carbons, four hydrogen and two oxygens. It has a carboxyl group which is represented by (−COOH). Acetic acid is formed when ethanol combines with oxygen in air, yielding ethanoic acid and water. This is called the oxidation of ethanol. It has no colour, but it has a sharp, strong odour very much like vinegar. Keep in mind this is a flammable chemical, with a flashpoint of 39degree Celsius. It is a volatile organic compound.
Note:
Methanamine is used for making paint removers, insecticides, pharmaceuticals, rubber chemicals etc. we can also call them methylamines, consisting of ammonia bearing a single methyl substituent. It has a role as a mouse.