Question
Biology Question on Significance Of Mitosis
Colchicine prevents the mitosis of cells at which of the following stage ?
A
Anaphase
B
Metaphase
C
Prophase
D
Interphase
Answer
Metaphase
Explanation
Solution
Colchicine is an alkaloid obtained from the plant Colchicum autumnale. During mitosis, it does not interfere with the replication of chromosome but prevents the formation of spindle fibres. During metaphase, it inhibits the assemblage of microtubules hence, spindle formation does not occur.