Question

Can a girl have Klinfelter’s syndrome?

Answer 1

The genetic disorder Klinefelter syndrome occurs when a male is born with an extra X chromosome. Because they have XXY chromosomes instead of the usual XY chromosomes seen in men, this disease is frequently referred to as XXY syndrome. In Klinefelter Syndrome, a trisomy of the X chromosome leads to an abnormal total of $47$ chromosomes (i.e.,$44 + XXY$ ) in each cell of the affected individual. This can occur due to the fusion of normal sperm ($22 + Y$ ) with abnormal trisomic ova ($22 + XX$ ).

Complete answer:
A girl can never be affected by Klinfelter’s syndrome.
Males are the only ones who are affected by Klinefelter's syndrome. Their karyotype is XXY because they have an additional X chromosome other than the typical XY. Overall, they are masculine, yet have feminine traits such as breast growth.
Since the genotype of a n individual affected with Klinfelter’s syndrome has a Y chromosome and with a genotype, the observed phenotype is always a male and not a female.

So, females usually do not show Klinfelter’s syndrome.

Additional information:
Symptoms of Klinfelter’s syndrome are as follows –
Sterility of males
Gynecomastia in males
Mental Retardation
He is tall and aggressive by nature.

Note:
Chromosomal Disorders – They are caused due to genomic mutations (Changes in chromosomal numbers) or due to chromosomal aberrations (Deletion, Duplication, Inversion, Translocation of chromosomal segments). Examples include Klinfelters syndrome and Turner's syndrome. Klinfelter’s syndrome is caused by the trisomy of the X chromosome. Trisomy is an example of an Aneuploid condition (Genomatic Mutation) where the chromosome number increases.