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Question: Statement I: For safe blood transfusion, recipient RBCs should not contain antibodies against antige...

Statement I: For safe blood transfusion, recipient RBCs should not contain antibodies against antigen on RBCs of donors.

Statement II: Blood grouping is based on the presence or absence of specific antigens on the surface of RBC's.

A

Both statement I and statement II are correct.

B

Both statement I and statement II are incorrect.

C

Statement I is correct but statement II is incorrect.

D

Statement I is incorrect but statement II is correct.

Answer

Statement I is incorrect but statement II is correct.

Explanation

Solution

Analysis of Statement I:

  • "For safe blood transfusion, recipient RBCs should not contain antibodies against antigen on RBCs of donors."

    • Blood safety during transfusion primarily depends on preventing the recipient's antibodies from reacting with the donor's antigens.
    • Antibodies are present in the plasma (serum) of the recipient, not on the surface of the recipient's RBCs. The recipient's RBCs carry their own specific antigens.
    • Therefore, the statement is incorrect because it incorrectly states that antibodies are present on recipient RBCs. The crucial factor is that the recipient's plasma should not contain antibodies that would react with the donor's RBC antigens.

Analysis of Statement II:

  • "Blood grouping is based on the presence or absence of specific antigens on the surface of RBC's."

    • This statement is correct. The ABO blood group system (A, B, AB, O) is determined by the presence or absence of A and B antigens on the surface of red blood cells. Similarly, the Rh blood group system (Rh positive or negative) is determined by the presence or absence of the Rh antigen (D antigen) on the surface of red blood cells.

Conclusion: Statement I is incorrect, and Statement II is correct.