Question

Both sickle cell anaemia and Huntington? chorea are

• A. bacteria-related diseases
• B. congenital disorders
• C. pollutant-induced disorders
• D. virus-related diseases

Answer 1

Answer: (B)

congenital disorders

Answer 2

Both sickle-cell anaemia and Hutingtons disease are congenital disorders, sickle-cell anaemia is the X-linked trait in which one $\beta$-chain of haemoglobin is different. $6^{\text {th }}$ amino acid of $\beta$-chain is valine instead of glutamic acid. Due to this patients haemoglobin level is reduced to half of the normal and person becomes anaemic. Huntingtons disease is also due to presence of repetetive motifs, which occurs due to repetition of few residues.