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Question

Pharmaceutical Chemistry Question on Solutions

Boric acid with molecular weight 61.83 was partitioned between water and amyl alcohol at 25 °C. The amount of boric acid was determined to be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The partition coefficient of boric acid between water and amyl alcohol, when calculated at molar concentration for each of the solution, is:

A

1.33

B

0.75

C

0.30

D

3.33

Answer

3.33

Explanation

Solution

The correct option is (D): 3.33