Question

Biotin is an organic compound present in yeast. It’s deficiency in the diet causes dermatitis and paralysis. It is also known as
A. Vitamin B1
B. Vitamin B12
C. Vitamin D
D. Vitamin H

Answer 1

Biotin is a part of the vitamin B family and it is a water soluble compound. Our body needs biotin to help convert some nutrients into energy and plays an important role in the health of your hair, skin, and nails. We get biotin from some dietary sources like Egg yolk, Salmon, Oats, Wheat, Dairy, Spinach, Rice, nuts, bananas, cauliflower, legumes etc.

Complete step by step answer:
Biotin is required for several purposes like
-Gluconeogenesis (New formation of Glucose)
-Branched-chain Amino Acid Catabolism
-Fatty Acid Synthesis
-Maintenance of skin, hair, and nail health
Biotin is also produced by the gut microbes in the gastro-intestinal system. Daily intake of biotin is ${\text{30mcg/day}}$.
It has a role as a prosthetic group, a coenzyme, a B vitamin, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, and a cofactor. It is a conjugate acid of a biotinate.
Causes for biotin deficiency:
-Poor diet intake
-Alcoholism
Consumption of raw egg whites (because there’s a substance called avidin in raw eggs which prevent the absorption of biotin in the body when consumed raw/uncooked).
-Malnutrition
-Inflammatory Bowel Disease which decreases the bacterial synthesis
-Too much intake of antibiotics.
-Smoking
-Genetic deficiency (biotinidase deficiency)
Biotin deficiency can lead to:
-Hair loss
-Scaly dermatitis
-Dry skin
-Depression
-Hallucinations
-Paraesthesia on extremities (numbness and tingling sensation) etc.
Biotin is also called as Vitamin B7, Vitamin H, Coenzyme R, anti-egg-white injury factor.
Thus, the correct option is D (Vitamin H).

Note:
Biotin is a carrier and a donor of carbon dioxide. So, biotin is required for carboxylation (i.e., it is a cofactor for carbon dioxide fixation). This is very important for protein synthesis and cell replication as well.