Question

Assertion: Diabetes insipidus is marked by excessive urination and too much thirst for water.
Reason: Antidiuretic hormone (ADH) is secreted by the posterior lobe of the pituitary.
A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.
B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.
C. Assertion is correct but Reason is incorrect
D. Both Assertion and Reason are incorrect.

Answer 1

Diabetes insipidus is medically defined as an uncommon disorder that causes an imbalance of fluids in the body of a human being. This imbalance makes the person extremely thirsty even if he has had something to drink. It also produces huge amounts of urine.

Complete step by step answer: The assertion is correct, as diabetes insipidus is a disorder that is caused by the absence of antidiuretic hormone (ADH), which is also called vasopressin. This hormone prevents dehydration, or the inability of the kidney to respond to ADH. ADH enables the kidneys to retain water in the body. The hormone is produced in the hypothalamus. It is both stored and released from the pituitary gland which is regulated by the hypothalamus. The first symptoms of diabetes insipidus include excessive thirst and urination.
-The reason is also correct but it is not the correct explanation of Assertion, as the amount of water that is conserved is managed by the antidiuretic hormone (ADH), which is also known as vasopressin. ADH is secreted by the posterior lobe of the pituitary gland that is a part of the hypothalamus. The drop in the level of ADH is the main reason for diabetes insipidus.
-Diabetes insipidus is seen mainly when the body of a person is unable to regulate how the fluid in the body is handled. It is caused due to a hormonal abnormality that is not related to diabetes. The other symptoms of diabetes insipidus include getting up at night to urinate, or bed-wetting. Depending on how serious the disorder is, the treatments include hormone therapy, a low-salt diet, and drinking plenty of water.
Therefore, we can say that Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.
Hence, the correct option is B.

Note: Diabetes insipidus is a permanent, lifelong disorder and cannot be cured that easily. However, the symptoms that contain constant thirst and urination can be controlled with treatment with DDAVP, which is a synthetic type of vasopressin. With the help of this normal, symptom-free quality of life can be restored.