Question

ASSERTION: Amount of cyanocobalamin required daily is 3 mcg.
REASON: Its deficiency causes pernicious anaemia
A. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
B. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
C. Assertion is correct but Reason is incorrect
D. Both Assertion and Reason are incorrect

Answer 1

Hint:- Cyanocobalamin is one of the vitamins in the b complex, and it is called as vitamin B12, and this is a water-soluble vitamin, which involves in various metabolism that occurs in every cell of the human body, and this vitamin act as a cofactor in various metabolism such as DNA synthesis, and other include fatty acid and amino acid metabolism.

Complete answer:
1. Vitamin B12 is the largest in structure and it is the most complex vitamin among all which occurs in four chemical forms, whereas in all forms of the vitamin B12, which contain a common biochemical compound that is cobalt, which is positioned in the center.
2. The organisms that naturally synthesize the vitamin B12 are bacteria and Archaea, and as we know that bacteria are found on various plants, and if these plants are eaten by the herbivores, by the time progress, this bacteria became the permanent bacteria in the intestine of the herbivores as the gut flora where it produces the cyanocobalamin internally.
3. Omnivores obtain this cyanocobalamin by taking animal sources such as food, meat, fish, etc.
4. And this vitamin can also be taken as supplements if it is necessary and they are available as tablets and injection forms.
5. Mainly there are two reasons for the vitamin B12 deficiency, as the cyanocobalamin absorption requires an intrinsic factor of the gastric juice for absorption so the depletion of this intrinsic factor or decrease in the secretion of gastric juice results in a deficiency of vitamin B12.
6. Vitamin B12 deficiency results in anemia called pernicious anemia, or it is also called megaloblastic anemia.
7. It also causes fatigue, lethargy, in case of any severe deficiency of this vitamin may cause irreversible damage to the brain and the nerves.
8. It also causes some gastrointestinal symptoms such as diarrhea or constipation or GAVE syndrome.
9. In children, it causes developmental delays.
10. And this deficiency is mainly seen in people who are under a strict vegetarian diet.
So the correct option is A.

Note:- Cyanocobalamin is commonly produced by the gut flora, but this absorption occurs only in the presence of intrinsic factor, and it is produced in the gastric juice and the deficiency of this vitamin results in pernicious anemia, and in case of severe deficiency it causes the severe damage of brain and nerves.