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Question

Pharmaceutics Question on Pre formulation

Arrange the following esters as per decreasing order of rate of saponification
(I) Ethyl benzoate
(II) Ethyl p-methoxybenzoate
(III) Ethyl p- chlorobenzoate
(IV) Ethyl p-nitrobenzoate

A

I>II>III>IV

B

IV>III>II>I

C

IV>II>I>II

D

II>IV>I>III

Answer

IV>II>I>II

Explanation

Solution

The correct option is (C) : IV>III>I>II