Question

Antigen-Antibody reactions are suppressed
(A) In liver dysfunction
(B) In chronic inflammatory reactions
(C) By ACTH
(D) By Vitamin-K

Answer 1

Immune system is a complex biological system that has the ability to recognize between self and foreign objects. Immunity is of two types: Innate Immunity and Adaptive Immunity. Innate immunity is present since birth while Adaptive immunity is acquired through the exposure of antigen, which triggers the release of antibodies by the immune system.

Complete answer:
Antigen and Antibody interact with each other leading to Antigen-Antibody reactions which is a specific chemical interaction between B-cells that produce antibody and antigen during an immune response. The combination of antigen and antibody is called agglutination.
The interaction between antigen and antibody involves Hydrogen bonds, Hydrophobic interaction, Electrostatic forces, and Van der Waal forces. These interactions can be influenced by several factors which include Temperature, pH, Ionic strength. In liver dysfunction, there is a high amount of antibody secretion by the liver, hence the antigen-antibody interaction will increase.
Chronic inflammatory conditions induce antigen-antibody reactions that cause immune response leading to inflammation.
ACTH is a pituitary hormone that secretes Cortisol. Cortisol prevents the release of antibodies, which causes suppression of antigen-antibody reactions.
Vitamin K is basically involved in the coagulation process, so it does not have much effect on the antigen-antibody reaction.

So, the correct answer is option (C) ACTH.

Note: Antigen-Antibody reactions are employed in the diagnosis of various diseases. They are used in the laboratory for serological testing. ABO Blood Grouping is also determined by the antigen-antibody reaction which is used in blood transfusion. ELISA also involves the use of antigen-antibody reaction for the diagnosis of various diseases.